Dr. Neelam Azad

SCIENTIFIC PAPERS

• Talbott S.J., Luanpitpong S., Stehlik C., Neelam Azad, Iyer A.K.V., Wang L., Rojanasakul Y. S-Nitrosylation of FLICE Inhibitory Protein Determines its Interaction with RIP1 and Activation of NF-kB. Cell Cycle (2014), 13(12), 948-957.

• Neelam Azad, Iyer A.K.V., Lu Y., Wang L., Rojanasakul Y. P38/MAPK Regulates Single-walled Carbon Nanotube-Induced Fibroblast Proliferation and Collagen Production. Nanotoxicology (2013),7(2), 157-168.

• Luanpitpong S., Iyer A.K.V., Neelam Azad, Wang L., Rojanasakul Y. Nitrosothiol Signaling in Anoikis Resistance and Cancer Metastasis. Forum on Immunopathological Diseases and Therapeutics (2012),3(2), 141-154.

• Djordje M., Luanpitpong S., Neelam Azad, Wang L., Jiang B. H., Davis M., Barnett J., Guo L., Rojanasakul Y. Multifunctional Role of Bcl-2 in Malignant Transformation and Tumorigenesis of Cr(VI)-Transformed Lung Cells. PLoS ONE (2012), 7(5), e37045.

• Iyer A.K.V., Neelam Azad, Wang L., and Rojanasakul Y. Cellular FLICE-Inhibitory Protein Regulates Fas-Ligand Induced Activation of NFκB in A PI3K-Dependent Manner. Journal of Immunology (2011), 187(6), 3256-66.

• Iyer A.K.V., Zhou M., Neelam Azad, Elbaz, H., Wang H., Rogalsky D., Rojanasakul Y., O’Doherty G. and Langenhan J. A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length Dependant Induction of Caspase-9-Mediated Apoptosis. American Chemical Society Medicinal Chemistry Letters (2010), 1(7), 300-369.

• Neelam Azad, Iyer A.K.V., Wang L., Lu Y., Medan D., Castranova V., Rojanasakul Y. Nitric Oxide-Mediated Bcl-2 Stabilization Potentiates Malignant Transformation of Human Lung Epithelial Cells. American Journal of Respiratory Cellular and Molecular Biology (2010), 42 (5), 578-585.

• Neelam Azad, Lu Y., Wang L., Iyer A.K.V., Castranova V., Jiang B.H., Rojanasakul Y. Phosphatidylinositol-3-Kinase/Akt Regulates Bleomycin-Induced Fibroblast Proliferation and Collagen Production. American Journal of Respiratory Cellular and Molecular Biology (2010), 42 (4), 432-441.

• Neelam Azad, Iyer A.K.V., Manosroi A., Wang L., Rojanasakul Y. Superoxide-Mediated Proteasomal Degradation of Bcl-2 Determines Cell Susceptibility to Cr(VI)-Induced Apoptosis. Carcinogenesis (2008), 29(8), 1538-1545.

• Iyer, A.K.V, Neelam Azad, Rojanasakul, Y. Role of S-nitrosylation in Apoptosis Resistance and Malignant Transformation. Nitric Oxide Biology and Chemistry (2008), 19(2), 146-151.

• Kongkaneramit L., Sarisuta N., Neelam Azad, Lu Y., Iyer A.K.V., Wang L., Rojanasakul Y. Dependence of Reactive Oxygen Species and FLIP on Lipofectamine-Induced Apoptosis in Human Lung Epithelial Cells. Journal of Pharmacology and Experimental Therapeutics (2008), 325(3), 969-977.

• Wang L., Neelam Azad, Kongkaneramit L., Chen F., Lu Y., Jiang B.H., Rojanasakul Y. The Fas Death Signaling Pathway Connecting Reactive Oxygen Species Generation and FLICE Inhibitory Protein Downregulation. Journal of Immunology (2008), 180(5), 3072-3080.

• Moungjaroen J., Nimmannit U., Callery P.S., Wang L., Neelam Azad, Lipipun V., Chanvorachote P., Rojanasakul Y. Reactive Oxygen Species Mediate Caspase Activation and Apoptosis Induced by Lipoic Acid in Human Lung Epithelial Cancer Cells through Bcl-2 Downregulation. Journal of Pharmacology and Experimental Therapeutics (2006), 319(3), 1062-1069.

• Neelam Azad, Vallyathan V., Wang L., Tantishaiyakul V., Stehlik C., Leonard S.S., Rojanasakul Y. S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation: A novel anti-apoptotic mechanism that suppresses apoptosis. The Journal of Biological Chemistry (2006), 281(45), 34124-34134.
   

• Chanvorachote P., Nimmannit U., Wang L., Stehlik C., Lu B., Neelam Azad, Rojanasakul Y. Nitric Oxide Negatively Regulates Fas CD95-induced Apoptosis through Inhibition of Ubiquitin-Proteasome mediated Degradation of FLICE Inhibitory Protein. The Journal of Biological Chemistry (2005), 280(51), 42044-42050.

SCIENTIFIC REVIEWS

• Iyer, A.K.V, Neelam Azad, Rojanasakul, Y. Nitrosothiol Signaling and Protein Nitrosation in Cell Death and    Survival. Nitric Oxide Biology and Chemistry (2014). [In press]

• Neelam Azad, Iyer A.K.V., Vallyathan V., Wang L., Castranova V., Stehlik C., Rojanasakul Y. Role of Oxidative/Nitrosative Stress-Mediated Bcl-2 Regulation in Apoptosis and Malignant Transformation. Annals of The New York Academy of Sciences (2010), 1203, 1-6.

• Neelam Azad, Rojanasakul, Y. and Vallyathan, V. Inflammation and Lung Cancer: Roles of Reactive Oxygen/Nitrogen Species. Journal of Toxicology and Environmental Health, Part B (2008), 11(1), 1-15.

• Neelam Azad, Rojanasakul Y. Nanobiotechnology in Drug Delivery. American Journal of Drug Delivery (2006), 4(2), 79-88.

• Neelam Azad, Rojanasakul Y. Vaccine Delivery - Current Trends and Future. Current Drug Delivery (2006), 3(2), 137-146.

BOOK CHAPTERS
 

• Neelam Azad, Iyer A. K. V. Reactive Oxygen Species and Apoptosis. Systems Biology of Free Radicals and Antioxidants (2014), 113-135.

• Iyer, A.K.V, Neelam Azad, Rojanasakul Y, Ma J.K.H. Application of Nanosciences in Pharmaceutics. Basic Physical Pharmacy (2012), 486-516.

• Iyer, A.K.V, Neelam Azad, Rojanasakul, Y. S-nitrosylation - How Cancer Cells Say NO to Cell Death. Nitric Oxide Biology and Chemistry, Prognosis, Prevention and Therapy (2010), Part 3, 4-102.

• Neelam Azad, Iyer A. K. V., Rojanasakul Y. Methods to Analyze S-nitrosylation of Proteins Involved in Apoptosis. Methods in Molecular Biology (2009), 559, 117-130.

• Neelam Azad, Iyer A. K. V., Rojanasakul Y. DNA Microarrays in Drug Discovery and Development. Biopharmaceutical Drug Design and Development (2007), 2nd Edition, 47-66.

• Neelam Azad, Rojanasakul Y. Macromolecular Drug Delivery. Biopharmaceutical Drug Design and Development (2007), 2nd Edition, 293-324.