Elucidate molecular mechanisms in cancer progression,
study the role of reactive oxygen and nitrogen species and establish
developmental models of malignant transformation.
Drug Discovery/Development
Assess the anti-tumor potential of various digitoxin
analogues and test their efficacy in in vivo models.
Angiogenesis
Study the crosstalk between various angiogenic
mediators that may play a critical role in driving angiogenesis in
various models, including fibrogenesis and carcinogenesis.
Toxicology
Assess the toxicological potential of single- and
multi-walled carbon nanoparticles and elucidate causalities of
nanoparticle pathogenesis in various disease states.
Stem Cells
Elucidate the mechanisms of cancer progression and
metastasis as mediated by cancer stem cells, and develop methods to
target them.
